In this paper, the relationship between socio-culture interaction and built environment was studied utilizing space syntax measurements (correlations between local and global spaces with relationship between connectivity and global integration). Intelligibility and synergy .These correlations were inspected utilizing Space Syntax. The city of AL-Khums was chosen as a case study because this area has had high values of intelligibility and synergy.  it was seen there was a solid correlation between local and global  integration and additionally between connectivity and global integration.. According to this correlations, a type of planning can increase intelligibility and synergy, interaction, Which in turn is reflected in the evolution of a good relations between inhabitants and visitors in urban spaces, and acceptance of others. The relationships between routes and spaces and their syntactic values are very important issues to find how spaces and streets affect socio-cultural interaction.

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